Group |
Mouse: BXD group |
Tissue |
Hippocampus mRNA |
Gene Symbol |
Nr3c1 |
Aliases |
Wikidata: GCRST; GR; GRL; GCR; GCCR; Grl-1; Grl1; Gcr; Grl |
|
GeneNetwork: GR; Grl1; Grl-1; GCR; GRL; GCCR; GCRST; GRA; GRB |
Location |
Chr 18 @ 39.410764 Mb on the minus strand |
Summary |
Enables several functions, including glucocorticoid receptor activity; identical protein binding activity; and protein kinase binding activity. Involved in positive regulation of pri-miRNA transcription by RNA polymerase II. Acts upstream of or within several processes, including gland development; glucocorticoid receptor signaling pathway; and regulation of cellular biosynthetic process. Located in cytosol; membrane; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and sensory organ. Used to study primary hyperaldosteronism. Human ortholog(s) of this gene implicated in several diseases, including anorexia nervosa; lung disease (multiple); major depressive disorder; obesity; and renal cell carcinoma. Orthologous to human NR3C1 (nuclear receptor subfamily 3 group C member 1). [provided by Alliance of Genome Resources, Apr 2022] |
Database |
Hippocampus Consortium M430v2 (Jun06) PDNN
|
Target Score |
BLAT Specificity
:
10.150
Score: 203.000
|
Resource Links |
Gene
OMIM
GeneMANIA
Protein Atlas
Rat Genome DB
GTEx Portal
UCSC
BioGPS
STRING
PANTHER
Gemma
ABA
EBI GWAS
|